The influence of industrial noise on urinary metanephrine, normetanephrine and vanilmandelic acid levels in workers of textile factory in Yazd, Iran

نویسندگان

  • Ali Eskandari
  • Farangis Gholami
  • Abolfazl Barkhordari
  • Seyedhossein Hekmatimoghaddam
چکیده

Noise, as the most common physical agent in workplace, not only causes hearing loss but also leads to various diseases, such as hypertension and cardiovascular disease. Sound is likely to stimulate and increase the secretion of adrenal catecholamines, and may have an indirect role in the pathogenesis of diseases caused by stress. This study was performed to investigate the effect of noise on urinary levels of metabolites of catecholamines of workers in a textile factory in Yazd, Iran. The sound pressure level was measured in different units of the factory, and the mill divided into two sections as noisy (leq≥ 85 db) and quiet (leq≤ 70 db) units. Forty four eligible workers participated in this study (22 as study and 22 as control group) and their urine samples were collected before and after workday shift. Metanephrine and normetanephrine levels were measured using enzyme linked immunosorbent assay (ELISA), and vanilmandelic acid level was measured using chromatography. Results were analyzed using Wilcoxon and Mann-Whitney statistical tests. Urinary levels of metanephrine, normetanephrine and vanilmandelic acid in the study group were significantly higher than control group in both before and after shift samples. In study group level of all three metabolites were significantly increased after workday shift. Although no significant after shift increase was observed for metanephrine and vanilmandelic acid in control group, but the increase in normetanephrine level was significant. It can be concluded that noise, as a stressor factor, may increase the excretion of catecholamines which may increase the risk of stressrelated diseases.

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تاریخ انتشار 2017